and the answer is....

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red

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Dimethyl sulfoxide (DMSO) is the chemical compound with the formula (CH3)2SO. This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a distinctive property of penetrating the skin very readily, allowing the handler to taste it. Some describe it as an "oyster-like" taste, others claim it tastes like garlic.



 

OH Breeder

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Is this correct

DMSO perhaps has been used most widely as a topical analgesic, in a 70 percent DMSO, 30 percent water solution. Laboratory studies suggest that DMSO cuts pain by blocking peripheral nerve C fibers.3 Several clinical trials have demonstrated its effectiveness,4,5 although in one trial, no benefit was found.6 Burns, cuts, and sprains have been treated with DMSO. Relief is reported to be almost immediate, lasting up to 6 hours. A number of sports teams and Olympic athletes have used DMSO, although some have since moved on to other treatment modalities. When administration ceases, so do the effects of the drug.

Dr. Jacob said at a hearing of the U.S. Senate Subcommittee on Health in 1980, "DMSO is one of the few agents in which effectiveness can be demonstrated before the eyes of the observers....If we have patients appear before the Committee with edematous sprained ankles, the application of DMSO would be followed by objective diminution of swelling within an hour. No other therapeutic modality will do this."

Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree they had not been able to obtain from any other source.

DMSO and Inflammation

DMSO reduces inflammation by several mechanisms. It is an antioxidant, a scavenger of the free radicals that gather at the site of injury. This capability has been observed in experiments with laboratory animals7 and in 150 ulcerative colitis patients in a double-blinded randomized study in Baghdad, Iraq.8 DMSO also stabilizes membranes and slows or stops leakage from injured cells.

 

DL

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OH B - DMSO is used extensively in horses both topically and (yup believe it or not!) IV - you can smell it a mile away when used either way -

It is classified as a prescription drug and therefore its use off label requires following the ELDU rules.

There has been a lot of research - much conflicting -about what it's properties are. It is used topically to decrease inflammation esp of the limbs - but also given IV to horses with neurological signs believed to be related to inflammation ( ie EPM). An additional use is a s a vehicle for other drugs and it will increase the absorption of other compounds. As far as I know it has never been studied in ruminants - therefore it would be impossible to determine a slaughter withdrawal - consequently its use in cattle would be considered verboten.

I can scan the 3 or 4 pages from the compendium if you want them - probably more than you want to know, was more than I wanted to know!
 

showcattlegal

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my horse got cute a couple of weeks ago and my vet put what they call yellow wonder on him. It's the yellow cream stuff mixed with dmso. Is that wrong?
 

DL

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showcattlegal said:
my horse got cute a couple of weeks ago and my vet put what they call yellow wonder on him. It's the yellow cream stuff mixed with dmso. Is that wrong?

NO!
For a couple of reasons the biggest one being that your horse is not a food animal! and so we don't consider withdrawal in non food animals (if you see some of the labels on horse drugs they say something like not intended for horses going to slaughter). The second reason it isn't wrong is that your vet gave you the stuff and I presume he labeled it.

My understanding of this whole gemish is that the primary concern is drug residue in food animals. The biggest reason for ELDU and AMDUCA is issues of food safety. Did that help?
 

red

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from what I read about DMSO is that it smells like garlic. Imagine it gets into the meat too w/ that smell & taste.

Red
 
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