There were may flushes of two TH carriers, before anyone knew anything about the defect. Personally, I have never intentionally flushed two carriers but I did two flushes using two TH carrier buls and had pregnancies due when I found out these bulls were carriers. I got very lucky. I had 6 ET calves from the one flush and I got 6 heifers. 5 of the 6 were TH free and 1 was a carrier. The 5 heifers averaged $6000 as calves and I still have the carrier. She has had 4 natural calves of which 3 were clean and 1 was a carrier... who was a bull and he went into the deep freeze.This year I decided I better use her as a recip and she has a ET calf due next spring The other flush I had to a carrier bull resulted in 4 calves born. Two heifers and two steers. Both steers were TH carriers and the 2 females were clean. All 4 were PHA free. I had 5 more embryos left from this flush and was debating if I should toss them out. I ended up putting them in one of my online embryo sales and I made it perfectly clear that the sire was a double carrier. I doubted if anyone would bid on them but they sold for $450 each or $2250.
I know there are several breeders that still have embryos from carrier sires and dams. If you like to gamble, you could probably buy them cheap. If you get a clean calf you could have a breeding piece. On the other hand, there are so many other clean choices I reaally don't know why anyone would do this.