DL said:
ELBEE said:
Found out yesterday from Agri-genomics office there should be a hydrocephalus test within the next 6 months. Found out today from Dr. Steffen's office that the defect described decades ago in the Shorthorn breed "is a unique phenotype from the ongoing hydrocephalus problem being investigated in the Angus breed". Just what we need 2 separate gene pools resulting in the same clinical defect. So if you cross a carrier Angus to a carrier Shorthorn you shouldn't see the defect until the offspring end up with both alees?
Lee - although they have the same name (hydrocephalus) they are not the same - the Shorthorn defect described in 1974 is what is called internal hydrocephalus and there are accompanying eye defects. The "hydro" described in Angus apparently the head is huge and there is no brain or spinal cord
theorhetically they could be in the same gene, just at different locations. if this is the case, it would be pretty difficult to get both defects on the same arm of the chromosome through a crossover just between them. if you had both alleles, it would be a double whammy.
this brings up rare crossover, accumulation of good snps and how difficult it is to gain two desirable snps in the same gene and why you can easily get an accumulation of them if a bull is popular for whatever reason and he propogates some good one's and some bad one's as 9j9 has done.
of course the defects could be two different genes too.
