I have thought about this most of the day, I think keeping replacements out of first calf heifers in most instances is ideal. 1. Greater chance for quicker genetic improvement. 2. Most heifers are from lighter birthweight genetics and are designed for calving ease, which should be an important trait on down the line when having subsequent calves. There are quite a few bulls now that produce small calves, but mature animals are adequately sized and have no problem having 85 to 100 lb calves on 2nd or 3rd calves 3. Most replacement heifers are bred to maternally oriented bulls, which have an increase in ability to mother. Most good clubby heifers and bulls have a great maternally oriented cow on the bottom side of their pedigree. 4. Decreased colostrum intake should only affect phenotype and not genotype as I am not aware of anything in colostrum that would alter a calf's DNA. It does however affect the Immuno response and that calf may not perform to its genetic potential. Most likely would be culled if its performance was below your expected performance. To quote Carroll Wright, "Figures Lie and Liars Figure"