Blog: A Steak in Genomics

[HerefordGuy]

A Steak in Genomics
Beef Improvement Federation 2016: Decker's thoughts on Dr. Keith Belk's presentation
http://blog.steakgenomics.org/2016/06/beef-improvement-federation-2016.html

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Feed Efficiency Genomics and RNA Project Discoveries
http://blog.steakgenomics.org/2016/06/bif-2016-feed-efficiency-genomics-and.html

BIF 2016: Effects of timing and duration of test period and diet type on intake and feed efficiency
http://blog.steakgenomics.org/2016/06/bif-2016-effects-of-timing-and-duration.html

BIF 2016: Gene set enrichment analysis for feed efficiency in beef cattle
http://blog.steakgenomics.org/2016/06/bif-2016-gene-set-enrichment-analysis.html

GeneSeek Meeting: The Value of Genomics
http://blog.steakgenomics.org/2016/06/geneseek-meeting-value-of-genomics.html

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Extension demonstration project outcomes; Industry adoption and translation of project deliverables
http://blog.steakgenomics.org/2016/06/bif-2016-extension-demonstration.html

 

[knabe]

A Steak in Genomics
BIF 2016: Extension demonstration project outcomes; Industry adoption and translation of project deliverables
http://blog.steakgenomics.org/2016/06/bif-2016-extension-demonstration.html

If tool doesn't work well across breeds, and not even red and black angus, I can imagine it not working in relatively closebred out cross angus. How do you describe the population where it works?

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: The 2016 and 2036 cow herd, what we do and what we need to do better
http://blog.steakgenomics.org/2016/06/bif-2016-2016-and-2036-cow-herd-what-we.html

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Extension demonstration project outcomes; Industry adoption and translation of project deliverables
http://blog.steakgenomics.org/2016/06/bif-2016-extension-demonstration.html

If tool doesn't work well across breeds, and not even red and black angus, I can imagine it not working in relatively closebred out cross angus. How do you describe the population where it works?

Just because you can imagine something, doesn't mean it is reality. See Deming quote.

Genomic prediction works well in breed-specific predictions.

We have data showing that genomic predictions can work in multiple-breed populations.

Scientific jargon warning:
Genomic predictions struggle across breeds due to many reasons, some of which likely include the more rapid break down of linkage disequilibrium in multiple-breed data sets (limited haplotype sharing across breeds especially at longer physical distances) and the fact the genetic interactions (epistasis) become more important across breeds.
End of scientific jargon.

 

[knabe]

You just described how it might work in different angus lines

No need for the faith versus reality reference. It interferes with your message. Really it just says anyone who I cant understand or disagree with is an idiot. It may seem clever but it undermines your effectiveness.

 

[HerefordGuy]

You just described how it might work in different angus lines

No need for the faith versus reality reference. It interferes with your message. Really it just says anyone who I cant understand or disagree with is an idiot. It may seem clever but it undermines your effectiveness.

No, it is meant to highlight that you make many claims without data. You are claiming that genomic prediction does not work across Angus lines. Where is the data?

The divergence between Angus lines is not strong enough to cause problems for genomic prediction. The Angus breed is basically a single population (panmictic, see supplement of http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-13-606). That is why we get strong correlations between genomic predictions and breeding values (see http://blog.steakgenomics.org/2016/03/angus-announces-routine-calibration-of.html).

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Growing profit by understanding cow maintenance efficiency and maintenance requirement in an animal and systems context
http://blog.steakgenomics.org/2016/06/bif-2016-growing-profit-by.html

 

[knabe]

I guess I had a question not a claim.

Really all I am saying is that germplasm diversity is disappearing and genomics is speeding that up. It may be gone before you find out you may need it.

 

[knabe]

I am clearly NOT making the claim that genomic prediction does not work across angus lines.

 

[librarian]

Really all I am saying is that germplasm diversity is disappearing and genomics is speeding that up. It may be gone before you find out you may need it.

We already need it.

 

[HerefordGuy]

I guess I had a question not a claim.

Really all I am saying is that germplasm diversity is disappearing and genomics is speeding that up. It may be gone before you find out you may need it.

I apologize for my misunderstanding.

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Can Beef Seedstock Producers Afford Genomics?
http://blog.steakgenomics.org/2016/06/bif-2016-can-beef-seedstock-producers.html

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Using genomic tools in commercial beef cattle: taking heifer selection to the next level.
http://blog.steakgenomics.org/2016/06/bif-2016-using-genomic-tools-in.html

 

[HerefordGuy]

A Steak in Genomics
BIF 2016: Genomics, return on investment - fact or fiction?
http://blog.steakgenomics.org/2016/06/bif-2016-genomics-return-on-investment.html

 

[HerefordGuy]

A Steak in Genomics
17th Annual Missouri Livestock Symposium December 2nd and 3rd
http://blog.steakgenomics.org/2016/08/17th-annual-missouri-livestock.html

 

[HerefordGuy]

A Steak in Genomics
ASA Simmental Fall Focus Teaming Technology with Tradition
Nuts and Bolts of Animal Breeding
http://blog.steakgenomics.org/2016/08/asa-fall-focus-nuts-and-bolts-of-animal.html

 

[HerefordGuy]

A Steak in Genomics
ASA Fall Focus BOLT
http://blog.steakgenomics.org/2016/08/asa-fall-focus-bolt.html

 

[HerefordGuy]

A Steak in Genomics
ASA Fall Focus: Taking Technology Home to the Farm and Ranch
http://blog.steakgenomics.org/2016/08/asa-fall-focus-taking-technology-home.html